First, we begin our culinary journey by preheating the oven to a toasty 400°F. While that warms up, let’s prepare our pie plate by greasing a medium glass pie plate (about 9 inches) with a bit of vegetable oil. This will ensure our pie doesn’t stick and comes out beautifully golden.

In a large skillet, heat some oil over medium heat and toss in the chopped onion. Sauté them until they are soft and fragrant, which should take about 3 minutes. Now, add the ground beef, breaking it apart with a spatula as it cooks. You want it browned, which should take about 10 minutes. Once it’s nice and brown, drain any excess fat from the pan. Now it’s time to season the beef! Sprinkle in the salt, ground black pepper, and, if you like, some garlic powder for that extra kick.

Next, let’s assemble our pie. Spread the cooked and seasoned beef mixture evenly into your prepared pie plate. Then, sprinkle the grated Cheddar cheese over the top, making it all melty and delightful. In a small bowl, whisk together the Bisquick mix (or flour), milk, and eggs until everything is well combined. Then pour this lovely batter over the beef and cheese layers in the pie plate.

Now, it’s time to bake! Place your pie in the preheated oven and let it cook for 20 to 25 minutes. You’ll know it’s done when a knife inserted in the center comes out clean. When it’s ready, take it out, let it cool a bit, and then slice yourself a piece of this comforting cheeseburger pie.